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SRM Bio Informatics - Sem VI
No Units Titles Sub Titles Chapters
1 Unit 1 Introduction Definition , Importance of Bioinformatics ,Biological Sequence Structure, Major databases in Bio Informatics, Molecular biology , Central Dogma, Data retrieval tools , Data mining of Databases , Gene Analysis , Prokaryotic and Eukaryotic Genomes , Sequence Assembly , Gene mapping , Physical maps , cloning , DNA, RNA sequences , Genetic code VIEW CHAPTERS
2 Unit 2 DNA And Protein Sequences Genome Information Resources , DNA Sequence data base , Specialised genomic Resources, DNA Sequence analysis: Why analyse DNA∞ , Gene structure , Features of DNA sequence analysis , Approaches to EST analysis , Effect of EST data on DNA data base examples of EST analysis, Protein,predicting properties , primary structure analysis , trans membrane segments , PROSITE patterns , interpreting scan prosite results, finding domains , CD server results , pfscan results VIEW CHAPTERS
3 Unit 3 Alignment Of Pair Of Sequences Terminology , Global and Local alignment , Dot matrix , dynamic programming using scoring matrices , PAM matrices , BLOSUM, Working with FASTA , Algorithm , output , E - values , Histogram working with BLAST algorithm, gapped BLAST, PSIBLAST , comparison of FASTA and BLAST VIEW CHAPTERS
4 Unit 4 Multiple Sequence Alignment Multiple Sequence Alignment : Goal , Definition , Consensus , Complex , methods , Database of multiple Alignment , searching database with multiple alignment, Methods of Photo Genetics,: Distance Based Methods , Based Methods , Comparison VIEW CHAPTERS
5 Unit 5 Protein Classification & Structure Prediction Structure of amino acids , primary structure , secondary structure , folds and motifs , alpha and beta helix , structure based protein classification , protein structure Data bases , folding problem , PROPSEARCH , primary structure analysis and prediction , secondary structure analysis and prediction , motifs , profiles , patterns and fingerprints VIEW CHAPTERS
 
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