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BDU Molecular Genetics Sem-III
No Units Titles Sub Titles Chapters
1 Unit 1 NA Principles of Mendelian inheritance, Chromosome structure and function- Organisation of chromosomes, specialized chromosomes, chromosome abnormalities- Numerical and structural changes in chromosomes, Epistasis, Linkage and crossing over - three point cross -tetrad analysis- chromosome mapping VIEW CHAPTERS
2 Unit 2 NA Human Chromosomes - Pedigree analysis, Mendelian traits and sex-linked traits in human -Population genetics - Hardy -Weinberg genetic equilibrium, Extra chromosomal inheritance (Episomes, Mitochondria and Chloroplast), Genetic polymorphism, Mechanism of sex determination VIEW CHAPTERS
3 Unit 3 NA DNA as the genetic material - RNA as a genetic material - replication of DNA and RNA,- The law of DNA constancy and C - value paradox- genetic code-Organization and function of prokaryotic and eukaryotic genetic material,- Organization of coding sequences and repetitive sequences- Molecular basis of spontaneous and induced mutations-DNA damage - mechanism of repair - excision repair, recombinational repair VIEW CHAPTERS
4 Unit 4 NA Viruses and their genetic system- Life cycles (lytic and lysogenic), RNA Phages, Retro viruses, Discovery of types and structure of plasmids - natural and artificial plasmid transfer and their applications, Insertion sequence in prokaryotes, Transposable elements - discovery and characterization,- Transposons in Bacteria, Maize, Yeast, - Insertional elements VIEW CHAPTERS
5 Unit 5 NA Genetic recombination- Transformation, transduction, sexduction and conjuagtion - linkage and genetic mapping in bacteria - genetic system of Neurospora, Regulation of Gene Expression In Prokaryotes And Eukaryotes- Operon concept- lac, trp, sigma factors-, promotor,operator, terminator and attenuator, DNA methylation- Hetero chroamatization-Environmental regulation of genes- Molecular genetics in relation to human diseases VIEW CHAPTERS
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