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Title :
MSc.CND102 Principles of Bio-Chemistry
Subject :
Clinical Nutrition and Dietetics
copyright © 2018 :
Karnataka State Open University
Author :
KSOU
Publisher :
Karnataka State Open University
Chapters/Pages :
16/369
Total Price :
Rs. : 270
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Foundation for Bio Chemistry
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Atom is the smallest unit of a substance. The identity of a substance will be destroyed if its atom is further divided. Different substances will have different types of atoms. All atoms are made up of a number of protons, neutrons and electrons. Molecule is the smallest unit of a compound. The water molecule consists of two hydrogen atoms and one oxygen atom which bind together by covalent bonds. ......
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13
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Water
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Water is the chemical substance with chemical formula H20: one molecule of water has two hydrogen atoms covalently bonded to a single oxygen atom. Water appears in nature in all three common states of matter and may take many different forms on Earth: water vapor and clouds in the sky; seawater and icebergs in the polar oceans;glaciers and rivers in the mountains; and the liquid in aquifers in the ......
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25
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Rs 18.75
Macromolecules
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General names for carbohydrates include sugars, starches, saccharides, and polysaccharides. The term saccharide is derived from the Latin word" sacchararum" from the sweet taste of sugars.
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26
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Carbohydrate Metabolism
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Carbohydrate metabolism begins with digestion in the small intestine where monosaccharides are absorbed into the blood stream. Blood sugar concentrations are controlled by three hormones: insulin, glucagon, and epinephrine. If the concentration of glucose in the blood is too high, insulin is secreted by the pancreas. Insulin stimulates the transfer of glucose into the cells, especially in the live ......
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35
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Elucidation of Structure of Proteins
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The first level is the amino acid sequence, often called its primary structure,perhaps to stress the fact that the sequence to a high degree defines the tertiary protein structure. The next level is the secondary structure, the primary building blocks of the tertiary protein structure. Secondary structure elements are combined into different structural motifs,or protein motifs, sometimes also call ......
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45
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Metabolism of Amino acids and Proteins
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The major portion of the metabolic, energy is generated by the oxidation of Carbohydrates and Triglycerides. Only a small portion of energy is furnished by the oxidation of amino acids . Amino acids are the building blocks for the biosynthesis of proteins and are the precursors of many biologically important nitrogen containing compounds, notably the physiologically active amines, glutathione, nuc ......
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26
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Lipids
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A lipid is defined as a water-insoluble biomolecule which has a high solubility in non polar organic solvents such as chloroform. The simplest lipids are the fats, which are triesters made up of one glycerol and three fatty acids. The term fats is also used as a general synonym for lipids, so the more precise terms triacylglycerols or triglycerides are preferable for the simplest lipids.
Pages:
24
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Metabolism of Lipids
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Lipids play an important role in cell structure and metabolism. TAGs are the major storage form of energy. Cholesterol is a component of cell membranes and precursor of steroid hormones. Lipid digestion occurs at lipid water interfaces since TAG is insoluble in water and digestive enzymes are water soluble. Lipids are digested and absorbed with the help of bile salts. Products of lipid digestion a ......
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24
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Enzymes
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The use of enzymes in the diagnosis of disease is one of the important benefits derived from the intensive research in biochemistry since the 1940's. Enzymes have provided the basis for the field of clinical chemistry. It is however, only within the recent past few decades that interest in diagnostic enzymology has multiplied.
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22
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Enzyme Inhibition
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Enzyme inhibitors are molecules that interact in some way with the enzyme to prevent it from working in the normal manner. There are a variety of types of inhibitors including: nonspecific, irreversible, reversible - competitive. and noncompetitive. Poisons and drugs are examples of enzyme inhibitors.
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22
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Enzyme Catalysis
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Enzyme catalysis is the catalysis of chemical reactions by specialized proteins known as enzymes. Catalysis of biochemical reactions in the cell is vital due to the very low reaction rates of the uncatalysed reactions.
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16
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Oxidative Stress and Antioxidants
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Oxidative stress represents an imbalance between the production and manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal redox state of tissues can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, includ ......
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15
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Nucleic Acids
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Nucleic acids are polymers of nucleotides held by 3' and 5' phosphate bridges. These serve as transmitters of genetic information. There are 2 types of nucleic acid DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).
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16
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Structure of Nucleic Acids
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Nucleic acids are biological molecules essential for life, and include DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). Together with proteins, nucleic acids make tip the most important macromolecules; each is found in abundance in all living things, where they function in encoding, transmitting and expressing genetic information. Nucleic acids were first discovered by Friedrich Miescher i ......
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13
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Central Dogma of Molecular Biology
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The three major steps in the processing of genetic information via the three fundamental processes of replication, transcription and translation is known as central dogma of molecular biology.
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14
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Genetic Code
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The genetic code is the set of rules by which information encoded in genetic material (DNA or mRNA sequences) is translated into proteins (amino acid sequences) by living cells. The code defines how sequences of three nucleotides, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three nucleotide codon in a nucleic acid sequence specifies ......
Pages:
33
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